Fumonisin B1 Levels Associated with an Epizootic of Equine Leukoencephalomalacia

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Eqüine leukoencephalomalacia and Fumonisin B

This article describes clinical, etiologic and pathologic diagnosis of an outbreak of equine leukoencephalomalacia. Two samples of the corn consumed by the affected horses contained fumonisin B 1 at levels of 46 and 53 μg/g and Fusarium moniliforme, a good in vitro mycotoxin producer.

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Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B1.

Leukoencephalomalacia (LEM) was induced by the oral administration of fumonisin B1 (FB1) to 2 horses: a filly received 59.5 mg/kg of a 50% preparation of FB1, administered in 21 doses of 1.25-4 mg/kg over 33 days; a colt, 44.3 mg/kg of 95% pure FB1 in 20 doses of 1-4 mg/kg in 29 days. Both animals developed nervous signs such as apathy, changes in temperament, inco-ordination, walking into obje...

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Leukoencephalomalacia in a horse induced by fumonisin B1 isolated from Fusarium moniliforme.

Each of two horses was dosed by stomach tube with culture material on maize of Fusarium moniliforme MRC 826. One horse developed severe hepatosis and mild oedema of the brain after 6 doses of 2.5 g of culture material/kg body mass/day in 7 days. The second horse, in a similar experiment but at a dosage rate of 1.25 g/kg/day, developed mild hepatosis and moderate oedema of the brain. In both ani...

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Genotyping of Fusarium verticillioides strains producing fumonisin B1 in feed associated with animal health problems

Fusarium verticillioides (F. verticillioides) is not only a primary pathogen of maize, but also can causedisease in other crops such as sorghum. Pathogenicity is related to mycotoxin production such as fumonisin.In the present study, 24 isolates of F. verticillioides, which were previously identified by phenotype basedmethods, were re-identified using restriction fragment length polymorphism (R...

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genotyping of fusarium verticillioides strains producing fumonisin b1 in feed associated with animal health problems

fusarium verticillioides (f. verticillioides) is not only a primary pathogen of maize, but also can causedisease in other crops such as sorghum. pathogenicity is related to mycotoxin production such as fumonisin.in the present study, 24 isolates of f. verticillioides, which were previously identified by phenotype basedmethods, were re-identified using restriction fragment length polymorphism (r...

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ژورنال

عنوان ژورنال: Journal of Veterinary Diagnostic Investigation

سال: 1990

ISSN: 1040-6387,1943-4936

DOI: 10.1177/104063879000200311